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Initially, three types of tumor-homing and cell-penetrating peptides (CPPs) are described, and then their applications in breast, glioma, colorectal, and melanoma cancer research are discussed

Viral-mediated gene delivery of IGF-1 has been shown to enable efficient transfer of IGF-1 into both young and adult animals

Abstract Hypoxia, a defining hallmark of solid tumors, arises from structurally and functionally abnormal vasculature, rapid cellular proliferation, and impaired perfusion, resulting in chronic and cycling oxygen deprivation within the tumor massThe hypoxic tumor microenvironment orchestrates extensive molecular reprogramming primarily through stabilization and activation of hypoxia-inducible factors (HIF-1 and HIF-2), which regulate broad transcriptional networks governing metabolism, angiogenesis, stemness, invasion, and immune modulation

SAS version 9.1 (SAS Institute Inc., Cary, NC, USA) was used for statistical analyses

After the drip You can return to work or normal activity immediately